Glucocorticoid-mediated establishment of an antiviral state coincident with other glucocorticoid-induced biochemical activities in L929 cells.

نویسندگان

  • G J Lancz
  • B A Hulick
  • R J Grasso
  • L Skinner
چکیده

Incubation of L929 cells with three different glucocorticoids, hydrocortisone, dexamethasone and triamcinolone acetonide, rendered the cells unable to support plaque formation by several unrelated DNA and RNA viruses. The establishment of this antiviral state by dexamethasone coincided with an inhibition of cell growth and induction of glutamine synthetase activity. These steroid-mediated activities occurred only in cultures of L929 cells and not in cultures of rabbit skin or rat glioma cells.

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عنوان ژورنال:
  • The Journal of general virology

دوره 66 ( Pt 10)  شماره 

صفحات  -

تاریخ انتشار 1985